Intraoperative floppy-iris syndrome and use of chronic oral tricyclic antidepressant

Intraoperative floppy-iris syndrome.

OBJECTIVE Intraoperative-floppy iris syndrome (IFIS) has been recently described. It has been demonstrated that this new syndrome complicates cataract surgery. In this paper we have reviewed the syndrome, and offer practical information specially related to the origin and management of this syndrome and we offer practical information. MATERIAL AND METHODS A review of the related medical liter...

The Intraoperative Floppy Iris Syndrome

A t the annual meeting of the ASCRS in April, John R. Campbell, MD, and I reported on two companion studies that we conducted to examine the incidence, characteristics, surgical outcomes, and etiology of floppy irides during cataract surgery.1,2 We named this condition the intraoperative floppy iris syndrome (IFIS) (Figures 1 to 3). Based upon retrospective observations by Dr. Campbell regardin...

Intraoperative floppy-iris syndrome associated with use of antipsychotic drugs.

OBJECTIVE We report 3 cases of intraoperative floppy-iris syndrome (IFIS) during cataract surgery in patients without a history of selective α1-blocker use but with a long-term history of antipsychotic drug use. We reviewed previously reported cases of antipsychotic drug-associated IFIS cases. DESIGN Observational case series. RESULTS In case 1, bilateral IFIS developed in a 39-year-old man...

Silodosin-associated intraoperative floppy iris syndrome

intraoperative floppy iris Syndrome : update 2012

α-BlOcKeRS anD iFiS Tamsulosin was reportedly introduced in Japan in 1993, in the United Kingdom in 1997, and in the United States in 1997. Gupta et al related the popularity of the drug to its high affinity for the α1A receptor, which explains the lower incidence of adverse cardiovascular events in patients taking tamsulosin compared with less selective α-adrenergic blockers.3 Additionally, th...